diff --git a/pre_commit/main.py b/pre_commit/main.py
index 3915993f..4ecee41b 100644
--- a/pre_commit/main.py
+++ b/pre_commit/main.py
@@ -165,7 +165,14 @@ def _adjust_args_and_chdir(args: argparse.Namespace) -> None:
     toplevel = git.get_root()
     os.chdir(toplevel)
 
-    args.config = os.path.relpath(args.config)
+    try:
+        args.config = os.path.relpath(args.config)
+    # https://github.com/pre-commit/pre-commit/issues/2530
+    # os.relpath will fail with a ValueError if the two directories are on
+    # two different drives on Windows and since the path is made relative
+    # for display purposes only we can ignore the error
+    except ValueError:
+        pass
     if args.command in {'run', 'try-repo'}:
         args.files = [os.path.relpath(filename) for filename in args.files]
         if args.commit_msg_filename is not None: